EXHIBIT 23

            Consent of Independent Registered Public Accounting Firm

     We consent to the incorporation by reference in the Registration Statements
(Forms S-3, No. 333-15533, 33-58736, 33-60229, 33-78760, 33-72170, 33-68542) and
(Forms S-8 No. 33-45348,  33-75466,  33-88826,  333-87153 and 333-89308) of Enzo
Biochem, Inc. and in the related Prospectus of our report dated October 7, 2004,
except  for Note 14 and the third  paragraph  of Note 7, as to which the date is
October 14,  2004 with  respect to the  consolidated  financial  statements  and
schedule of Enzo  Biochem,  Inc.  included in this Annual Report (Form 10-K) for
the fiscal year ended July 31, 2004.



                                                  /s/  Ernst & Young LLP





Melville, New York
October 14, 2004