EXHIBIT 23

            Consent of Independent Registered Public Accounting Firm

We consent to the  incorporation  by  reference in the  Registration  Statements
(Forms S-3, No. 333-15533, 33-58736, 33-60229, 33-78760, 33-72170, 33-68542) and
(Forms  S-8  No.  33-45348,   33-75466,  33-88826,   333-87153,   333-89308  and
333-123712)  of Enzo Biochem,  Inc. and in the related  Prospectus of our report
dated October 12, 2005, with respect to the  consolidated  financial  statements
and  schedule  of  Enzo  Biochem,  Inc.  ,  Enzo  Biochem,  Inc.'s  management's
assessment of the  effectiveness of internal  control over financial  reporting,
and the  effectiveness  of internal  control  over  financial  reporting of Enzo
Biochem,  Inc.  included in this Annual  Report  (Form 10-K) for the fiscal year
ended July 31, 2005.


                                               /s/  Ernst & Young LLP




Melville, New York
October 12, 2005