Form: 10-K

Annual report pursuant to Section 13 and 15(d)

October 30, 1995

EXHIBIT 12

Published on October 30, 1995



EXHIBIT 12

ENZO BIOCHEM, INC.
COMPUTATION OF RATIO OF EARNINGS
TO FIXED CHARGES
Years ended July 31, 1995, 1994, 1993, 1992 and 1991




1995 1994 1993 1992 1991
---- ---- ---- ---- ----


Fixed charges:
Interest (including capitalized interest and
amortization of deferred financing costs of
$0 and $0 in 1995, $0 and $0 in 1994, $0 and
$2,400 in 1993, $450,000 and $69,000 in 1992,
and $1,598,000 and $167,000 in 1991,
respectively) $136,000 $114,000 $256,000 $2,273,000 $5,154,000

Portion of rental expense representative of
interest 377,000 369,000 346,000 353,000 438,000
----------- ---------- ----------- ---------- ------------
Total fixed charges $513,000 $483,000 $602,000 $2,626,000 $5,592,000
----------- ---------- ----------- ---------- ------------
----------- ---------- ----------- ---------- ------------

Earnings
Income (loss) before provision (benefit) for
taxes on income and extraordinary items $9,749,000 $2,156,000 $(6,324,000) $(1,103,000) $(10,764,000)
Extraordinary items -- 150,000 (466,000) 572,000 (790,000)
----------- ---------- ----------- ---------- ------------
9,749,000 2,306,000 (6,790,000) (531,000) (11,554,000)

Total fixed charges 513,000 483,000 602,000 2,626,000 5,592,000
Less capitalized interest -- -- -- (450,000) (1,598,000)
----------- ---------- ----------- ---------- ------------
Total earnings (loss) $10,262,000 $2,789,000 $(6,188,000) $1,645,000 $(7,560,000)
----------- ---------- ----------- ---------- ------------
Deficiency of earnings to cover fixed charges -- -- $(6,790,000) $(981,000) $(13,152,000)
----------- ---------- ----------- ---------- ------------
----------- ---------- ----------- ---------- ------------

Ratio of earnings to cover fixed charges 20.00 5.77 -- -- --
----------- ---------- ----------- ---------- ------------
----------- ---------- ----------- ---------- ------------




E-16