Annual report pursuant to Section 13 and 15(d)


Cover - USD ($)
12 Months Ended
Jul. 31, 2021
Nov. 22, 2021
Jan. 31, 2021
Cover [Abstract]      
Document Type 10-K/A    
Amendment Flag true    
Amendment Description Enzo Biochem, Inc. (the “Company”) is filing this Amendment No. 2 (this “Form 10-K/A”) to Form 10-K for the fiscal year ended July 31, 2021, that we originally filed with the Securities and Exchange Commission (the “SEC”) on October 12, 2021, and as amended by the Amendment No. 1 to Form 10-K filed on November 29, 2021 (as so amended, the “original 10-K”).   This Form 10-K/A has been prepared and filed solely to (i) amend Item 10 of the original Form 10-K to reflect the current membership of the Board’s committees, (ii) amend Item 12 of the original Form 10-K to correct the inadvertent omission of Dov Perlysky from the table reflecting Beneficial Ownership of Principal Shareholders and Management, and (iii) to make other conforming changes.   Except as described above, no other changes have been made to the original Form 10-K. The original Form 10-K continues to speak as of October 12, 2021, the date the Company filed the original Form 10-K with the SEC, and other than as expressly indicated in the original Form 10-K or in this Form 10-K/A, the Company has not updated the disclosures contained therein to reflect any events that have occurred at a date subsequent to October 12, 2021.  Accordingly, this Form 10-K/A should be read in conjunction with the original Form 10-K and the Company’s other reports filed thereafter.    
Document Annual Report true    
Document Transition Report false    
Document Period End Date Jul. 31, 2021    
Document Fiscal Period Focus FY    
Document Fiscal Year Focus 2021    
Current Fiscal Year End Date --07-31    
Entity File Number 001-09974    
Entity Registrant Name Enzo Biochem, Inc.    
Entity Central Index Key 0000316253    
Entity Tax Identification Number 13-2866202    
Entity Incorporation, State or Country Code NY    
Entity Address, Address Line One 527 Madison Ave.    
Entity Address, City or Town New York    
Entity Address, State or Province NY    
Entity Address, Postal Zip Code 10022    
City Area Code 212    
Local Phone Number 538-0100    
Title of 12(b) Security Common Stock, $.01 par value    
Trading Symbol ENZ    
Security Exchange Name NYSE    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
Entity Shell Company false    
Entity Public Float     $ 126,324,000
Entity Common Stock, Shares Outstanding   48,471,771